Highly Enantioselective Catalytic Conjugate Addition and Tandem Conjugate Addition–Aldol Reactions of Organozinc Reagents
نویسندگان
چکیده
منابع مشابه
Copper-catalyzed Enantioselective Conjugate Addition Reactions of Organozinc Reagents
Conjugate addition (1,4-addition) of carbon nucleophiles to a; b-unsaturated compounds is one of the most important carbon–carbon bond-forming strategies in synthetic organic chemistry [1]. The versatility of the conjugate addition is mainly due to the large variety of nucleophiles (organometallic reagents, Michael donors, other carbanions) and acceptors (a; b-unsaturated aldehydes, ketones, ni...
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The addition of nucleophiles to electron-deficient alkenes represents one of the more general and commonly used strategies for the convergent assembly of more complex structures from simple precursors. In this review the addition of diverse protic and organometallic nucleophiles to electron-deficient alkenes followed by enantioselective protonation is summarized. Reactions are first categorized...
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition in English
سال: 1997
ISSN: 0570-0833,1521-3773
DOI: 10.1002/anie.199726201